As the great romcom queen turns 60, we select her best roles from the low-budget indies to the Tom Hanks big-hitters

By 2007, Meg Ryan was already well into a wilderness period that still hasn’t ended. Indeed, it has been more than five years since she was in a film at all (Ithaca, her harmless but forgettable directorial debut). If highlights of this era have been few, her restrained, affecting turn as an unhappily married, cancer-stricken housewife in this uneven indie soap opera was a reminder that the industry did her dirty. At the very least, more little films like this could use her wattage.

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